TOS ran 1966-june3rd1969, Russia first landed unmanned in 1959, and the human race through NASA and the Apollo program first landed on the moon on june 20th 1969

Isaac Asimov was a biochemist born in 1920, started writing published sci-fi in 1939 and full on scifi novels in 1950 (seriously, this stuff was wayyyyy ahead of its time). Died in 1992.

Gene Roddenberry was born in 1921, died in 1991.