Comment on Can harmless viruses be engineered to deliver vaccine payloads for different actually harmful viruses?

e0qdk@reddthat.com ⁨4⁩ ⁨days⁩ ago

Yes. There are virus vector vaccines already in existence: en.wikipedia.org/wiki/Viral_vector_vaccine

For example, adenovirus vector vaccines were created for COVID-19: en.wikipedia.org/wiki/COVID-19_vaccine#Adenovirus…

Those are non-replicating though.

Live attenuated vaccines also exist – which can replicate – but those work by using a weakened/modified version of the original harmful live virus the vaccine is intended to protect against: en.wikipedia.org/wiki/Attenuated_vaccine

Oral polio vaccine is a well-known example.

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