I… think this question is a bit more complicated for this community. Following are only my personal opinion

Prescribed medication? I think so, I’d rather be physically and mentally healthy rather than have the other alternative. And usually medication (even ones with noted negative effects) are meant do do more good than harm so…

Recreational drugs… the line between this and the above is surprisingly not as clear-cut as it seems. I believe there are active lines of study of using various psychedelic compounds to treat mental disorders or other conditions… Personally I would take medically prescribed psychedelics if I am 1) under medical supervision and 2) based on evidence it would help my mental health (maybe that’s the answer to the question?)

Hard drugs: I don’t see how they can make anyone a better person, and no